To start an software you have to pass the affinity flag to the start utility in the command prompt.
The only drawback to this approach is that the command prompt window will briefly flash on the screen.
Start an Application Assigned to a Specific CPU in Windows 7, 8, or Vista
Windows has an option that lets you start an application and set the CPU affinity, which assigns the application to run on a specific CPU in a dual-core system.
